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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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Human TAX1BP3 Protein (Recombinant His) - LS-G20378
TAX1BP3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 144 amino acids (1-124 a.a.) and having a molecular mass of 15.8kDa.TAX1BP3 is fused to a 20 amino acid His-tag at N-terminus and purified by proprietary chromatographic techniques.
E. coli
E. coli
His
Greater than 95% by SDS-PAGE
Not Tested
Not Tested
20 mM Tris-HCl, pH 8.0, 20 mM DTT, 20 mM NaCl, 20% glycerol.
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
TAX1BP3 Protein, Tax-interacting protein 1 Protein, Tax1-binding protein 3 Protein, Tax interaction protein 1 Protein, TIP-1 Protein, TIP1 Protein
May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.
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