Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Recombinant Human ST13 produced in E.Coli is a single,non-glycosylated polypeptide chain containing 369 amino acids (12-369 a.a.) and having a molecular mass of 41.3 kDa.ST13 human recombinant is purified by convential chromatogrpahy techniques.
Greater than 90% by SDS-PAGE
20 mM Tris-HCl, pH 8, 20 mM DTT, 20 mM NaCl, 10% glycerol.
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
ST13 Protein, Aging-associated protein 2 Protein, AAG2 Protein, Hsc70-interacting protein Protein, HSPABP1 Protein, HOP Protein, Hsp70-interacting protein Protein, HSPABP Protein, FAM10A1 Protein, HIP Protein, p48 Protein, PRO0786 Protein, Protein FAM10A1 Protein, Putative tumor suppressor ST13 Protein, SNC6 Protein, FAM10A4 Protein
One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins.