Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Purified / Lyophilized / Endotoxin Level: Less than 1.0 EU/µg protein (determined by LAL method).
SSR1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain topological domain containing 209 amino acids (22-207 a.a) and having a molecular mass of 23.1kDa. SSR1 is fused to a 23 amino acid His-tag at N-terminus and purified by proprietary chromatographic techniques.
Greater than 90% by SDS-PAGE
20 mM Tris-HCl, pH 8.0, 20 mM NaCl, 20 mM DTT, 20% glycerol.
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
SSR1 Protein, Signal sequence receptor Protein, SSR-alpha Protein, TRAP-alpha Protein, TRAP alpha Protein, Ssr Protein, SSR alpha subunit Protein, Trap-a Protein, TRAPA Protein
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human alpha-signal sequence receptor gene (SSR1), also referred to as TRAP alpha, maps to the short arm of chromosome 6. SSR1 has several mRNA species as a result of complex alternative polyadenylation.