LSBio The Immunohistochemistry Antibody Company
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All ELISA Kits
  • Traditional ELISA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Phospho-Specific ELISA Kits
  • ELISA Development Kits
  • Chemiluminescent CLIA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question?
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Protocols
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Contact Us

2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products. - To submit a new order. - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues. - To request technical information requests about an LSBio product or its application. - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Human SIRT5 / Sirtuin 5 Recombinant (His) Protein (aa1-310) - LS-G3823


Wt. Vol. Conc. Price
10 µg - - Unavailable
50 µg - - Unavailable

Most Popular SIRT5 / Sirtuin 5 Proteins

Human SIRT5 / Sirtuin 5 Recombinant (His) Protein - LS-G2655
E. coli Expression System
300 AA
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human SIRT5 / Sirtuin 5 Recombinant (His) Protein (aa1-310) - LS-G3823
E. coli Expression System
Purified / Biologically Active / Endotoxin Level: Less than 1.0 EU/µg protein (determined by LAL method).
Functional Assay Image
Human SIRT5 / Sirtuin 5 Recombinant (His) Protein (aa37-310) - LS-G3828
E. coli Expression System
Purified / Biologically Active
Functional Assay Image
Human SIRT5 / Sirtuin 5 Recombinant (GST) Protein - LS-G5403
E. coli Expression System
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Mouse SIRT5 / Sirtuin 5 Recombinant (His) Protein (aa37-310) - LS-G15586
E. coli Expression System
Purified / Lyophilized

100% Guaranteed 100% Guaranteed
Recombinant Protein
SIRT5 / Sirtuin 5
~40kDa (SDS-PAGE)
Human sirtuin 5 (aa 1-310) is fused at the N-terminus to a His-tag.
aa 1-310
E. coli
E. coli
Greater than 90% by SDS-PAGE
HDAC activity.
Less than 1.0 EU/µg protein (determined by LAL method).
55 mM Tris-HCl, pH 8.2, 150 mM NaCl
Store at +4°C for immediate use, or aliquot and store at -20°C for up to 3 months. Avoid repeat freeze-thaw cycles.
For research use only.

About SIRT5 / Sirtuin 5

Q9NXA8 NM_031244 NP_112534.1

SIRT5 Protein, SIR2L5 Protein, Sir2-like 5 Protein, SIR2-like protein 5 Protein, Sirtuin 5 Protein, Sirtuin type 5 Protein

NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species.

Functional Assay

Functional Assay
HDAC activity (HDAC Fluorimetric Assay -AK-500 from ELS). This assay is performed in two stages. In the first stage, the HDAC(s) acts on the Substrate (10 uM, 50 uM) (total volume of 50 ul). The second stage, is initiated by the addition of 50 ul of developer, stops HDAC activity and produces the fluorescent signal. The samples are read in a microplate reading fluorimeter, capable of excitation at a wavelength in the range 350~380nm and detection of emission light in the range 440~460nm.

Requested From: 
Date Requested: 4/25/2017

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2017 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number