Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
SGOL1 Protein, NY-BR-85 Protein, Shugoshin 1CD protein Protein, Shugoshin 1EF protein Protein, Shugoshin-like 1 (S. pombe) Protein, SGO Protein, Sgo1 Protein, Shugoshin 1AB protein Protein, Shugoshin 1KL protein Protein, Shugoshin-like 1 Protein, HSgo1 Protein, Shugoshin Protein, Shugoshin 1GH protein Protein
Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the STAG2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by ESPL1/separase at anaphase.