Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
FRZB Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 316 amino acids (33-325 a.a) and having a molecular mass of 35kDa.FRZB is fused to a 23 amino acid His-tag at N-terminus and purified by proprietary chromatographic techniques.
Greater than 90% by SDS-PAGE
20 mM Tris-HCl, pH 8.0, 20 mM Urea, 10% glycerol.
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
FRZB Protein, FRZB-1 Protein, FIZ Protein, FRE Protein, FRITZ Protein, Fritz and frizzled Protein, Frizzled homolog-related Protein, FRP-3 Protein, FRZB-PEN Protein, HFIZ Protein, FRP Protein, FZRB Protein, SFRP-3 Protein, SRFP3 Protein, OS1 Protein, Frezzled Protein, Frizzled related protein 3 Protein, Frizzled-related protein Protein, Frizzled-related protein 1 Protein, FRZB1 Protein, SFRP3 Protein
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.