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Human SERPING1 / C1 Inhibitor Recombinant Protein LS-G125

Ordering

Wt. Vol. Conc. Price
50 µg - - $215
200 µg - - $285
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SERPING1 / C1 Inhibitor Proteins

Human SERPING1 / C1 Inhibitor Native Protein - LS-G5075
Human Expression System
None
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human SERPING1 / C1 Inhibitor Recombinant (6His,C-terminus) Protein - LS-G39044
Human Human Cells
6His,C-terminus
Unpurified
Mouse SERPING1 / C1 Inhibitor Recombinant (6His,C-terminus) Protein - LS-G39969
Human Human Cells
6His,C-terminus
Unpurified

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LS-G125
Recombinant Protein
SERPING1 / C1 Inhibitor
Human
49.4 kDa
Recombinant protein encodes amino acids 23-500 of C1 inhibitor precursor.
VEPILEVSSL PTTNSTTNSA TKITANTTDE PTTQPTTEPT
TQPTIQPTQP TTQLPTDSPT QPTTGSFCPG PVTLCSDLES
HSTEAVLGDA LVDFSLKLYH AFSAMKKVET NMAFSPFSIA
SLLTQVLLGA GENTKTNLES ILSYPKDFTC VHQALKGFTT
KGVTSVSQIF HSPDLAIRDT FVNASRTLYS SSPRVLSNNS
DANLELINTW VAKNTNNKIS RLLDSLPSDT RLVLLNAIYL
SAKWKTTFDP KKTRMEPFHF KNSVIKVPMM NSKKYPVAHF
IDQTLKAKVG QLQLSHNLSL VILVPQNLKH RLEDMEQALS
PSVFKAIMEK LEMSKFQPTL LTLPRIKVTT SQDMLSIMEK
LEFFDFSYDL NLCGLTEDPD LQVSAMQHQT VLELTETGVE
AAAASAISVA RTLLVFEVQQ PFLFVLWDQQ HKFPVFMGRV
YDPRA
CHO Cells
Hamster-Chinese
None
Greater than 95% by SDS-PAGE and HPLC
Measured by its ability to inhibit recombinant human complement component C1a cleavage of a colorimetric peptide substrate, N Carbobenzyloxy-Lys-ThioBenzyl ester (Z-K-SBzl). The expected IC50 is <=2.6 nM.
Less than 0.1 ng/µg of protein (less than 1EU/µg).
Sterile filtered, lyophilized from 10 mM sodium phosphate, pH 7.5
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
If lyophilized, can be stored for 1 month at room temperature, 6 months at 4°C, or through the expiration date at -20°C to -80°C. Once reconstituted per the supplied instructions, can be stored for 3 months at -20°C to -80°C, or for 1 week at 2°C to 8°C. Avoid repeat freeze-thaw cycles.
For research use only.

About SERPING1 / C1 Inhibitor

P05155 NM_000062 NP_000053.2

SERPING1 Protein, C1-inhibiting factor Protein, C1IN Protein, C1 Inh Protein, C1-INH Protein, C1INH Protein, C1NH Protein, C1 Inhibitor Protein, HAE1 Protein, HAE2 Protein, Plasma protease C1 inhibitor Protein, C1 esterase inhibitor Protein, Serpin G1 Protein

Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein.

Requested From: United States
Date Requested: 12/6/2016

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