Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
SEC13 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 342 amino acids (1-322 a.a.) and having a molecular mass of 37.7kDa. The SEC13 is purified by proprietary chromatographic techniques.
Greater than 95% by SDS-PAGE
20 mM Tris-HCl, pH 8.0, 20 mM DTT, 10% glycerol, 20 mM NaCl.
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
SEC13 Protein, D3S1231E Protein, Protein SEC13 homolog Protein, SEC13-like 1 isoform Protein, SEC13R Protein, SEC13 (S. cerevisiae)-like 1 Protein, SEC13 homolog (S. cerevisiae) Protein, SEC13-like 1 (S. cerevisiae) Protein, SEC13-like protein 1 Protein, SEC13-related protein Protein, SEC13L1 Protein, Npp-20 Protein
Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. As a component of the GATOR2 complex, inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway.