Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
PPM1G Human Recombinant fused with His-tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 250 amino acids and having a molecular mass of 27 kDa.The PPM1G is purified by proprietary chromatographic techniques.
Greater than 95% by SDS-PAGE and HPLC
25 mM Tris pH 7.5, 25 mM DTT, 25 mM EDTA, 25 mM b-ME, 20% glycerol.
PPM1G Protein, Phosphatase fin13 Protein, PP2CG Protein, PP2C-gamma Protein, Protein phosphatase 1C Protein, PP2C, gamma Protein, PP2CGAMMA Protein, PPM1C Protein, PPP2CG Protein, Protein phosphatase 2c gamma Protein, Protein phosphatase 1G Protein
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.