Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
PRKG1 Protein, CGKI Protein, CGMP kinase I Protein, CGMP protein kinase type I Protein, CGK-I Protein, CGK1 Protein, PKGI Protein, PKG I Protein, PRKGR1B Protein, PRKG1B Protein, PRKGR1A Protein, PGK Protein, PKG Protein, CGK Protein, CGK 1 Protein, CGKI-alpha Protein, CGKI-BETA Protein
Serine/threonine protein kinase that acts as key mediator of the nitric oxide (NO)/cGMP signaling pathway. GMP binding activates PRKG1, which phosphorylates serines and threonines on many cellular proteins. Numerous protein targets for PRKG1 phosphorylation are implicated in modulating cellular calcium, but the contribution of each of these targets may vary substantially among cell types.