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Human PARP1 Recombinant Protein - LS-G43436

Ordering

Wt. Vol. Conc. Price
5 µg - - Unavailable

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100% Guaranteed 100% Guaranteed
LS-G43436
Recombinant Protein
PARP1
Human
MKSKLPKPVQ DLIKMIFDVE SMKKAMVEYE IDLQKMPLGK
LSKRQIQAAY SILSEVQQAV SQGSSDSQIL DLSNRFYTLI
PHDFGMKKPP LLNNADSVQA KAEMLDNLLD IEVAYSLLRG
GSDDSSKDPI DVNYEKLKTD IKVVDRDSEE AEIIRKYVKN
THATTHNAYD LEVIDIFKIE REGECQRYKP FKQLHNRRLL
WHGSRTTNFA GILSQGLRIA PPEAPVTGYM FG
E. coli
None
Greater than 95% by SDS-PAGE
20 mM, Tris, pH 8, 1 mM DTT, 10% glycerol
For research use only.

About PARP1

P09874 NM_001618 NP_001609.2

PARP1 Protein, ADPRT Protein, ADP-ribosyltransferase NAD(+) Protein, Adp-ribosyltransferase Protein, ADPRT1 Protein, ARTD1 Protein, ADPRT 1 Protein, Poly(ADP-ribose) synthetase Protein, Poly(ADP-ribosyl)transferase Protein, PARP Protein, Poly [ADP-ribose] polymerase 1 Protein, PADPRT-1 Protein, PARP-1 Protein, Poly (ADP-ribose) polymerase 1 Protein, Poly(ADP-ribose) polymerase Protein, Poly[ADP-ribose] synthase 1 Protein, PPOL Protein

Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates the poly(ADP-ribosyl)ation of APLF and CHFR.

Requested From: 
Date Requested: 4/26/2017

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