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Human NR1H4 / FXR Protein (Recombinant His + SUMO) (aa1-476) - LS-G21829

Catalog Size Price
LS-G21829-50 50 µg Unavailable
LS-G21829-200 200 µg Unavailable
LS-G21829-500 500 µg Unavailable
LS-G21829-1000 1000 µg Unavailable

Most Popular NR1H4 / FXR Proteins

Human NR1H4 / FXR Protein (Recombinant His + SUMO) (aa1-476) - LS-G21829
E. coli Expression System
476 AA
His + SUMO
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human NR1H4 / FXR Protein (Recombinant His + GST + S) - LS-G24613
E. coli Expression System
His + GST + S
Lyophilized
Rat NR1H4 / FXR Protein (Recombinant His + GST) - LS-G24614
E. coli Expression System
His + GST
Lyophilized
Human NR1H4 / FXR Protein (Recombinant GST) - LS-G31879
Wheat Wheat Germ Extract
476 AA
GST
Purified
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

100% Guaranteed
LS-G21829
Recombinant Protein
NR1H4 / FXR
Human
70.8 kD
aa 1-476
MGSKMNLIEH SHLPTTDEFS FSENLFGVLT EQVAGPLGQN
LEVEPYSQYS NVQFPQVQPQ ISSSSYYSNL GFYPQQPEEW
YSPGIYELRR MPAETLYQGE TEVAEMPVTK KPRMGASAGR
IKGDELCVVC GDRASGYHYN ALTCEGCKGF FRRSITKNAV
YKCKNGGNCV MDMYMRRKCQ ECRLRKCKEM GMLAECMYTG
LLTEIQCKSK RLRKNVKQHA DQTVNEDSEG RDLRQVTSTT
KSCREKTELT PDQQTLLHFI MDSYNKQRMP QEITNKILKE
EFSAEENFLI LTEMATNHVQ VLVEFTKKLP GFQTLDHEDQ
IALLKGSAVE AMFLRSAEIF NKKLPSGHSD LLEERIRNSG
ISDEYITPMF SFYKSIGELK MTQEEYALLT AIVILSPDRQ
YIKDREAVEK LQEPLLDVLQ KLCKIHQPEN PQHFACLLGR
LTELRTFNHH HAEMLMSWRV NDHKFTPLLC EIWDVQ
E. coli
E. coli
His + SUMO
Not Tested
Not Tested
Tris buffer, 50% glycerol.
Long term: -80°C; Short term: -20°C. Avoid freeze-thaw cycles.
For research use only.

About NR1H4 / FXR

Q96RI1 NM_005123 NP_005114.1

NR1H4 Protein, BAR Protein, Farnesyl x receptor Protein, FXR Protein, HRR1 Protein, Farnesoid x activated receptor Protein, Farnesoid X receptor Protein, Farnesol receptor HRR-1 Protein, HRR-1 Protein, RXR-interacting protein 14 Protein, RIP14 Protein, Bile acid receptor Protein, Farnesoid X nuclear receptor Protein, Farnesoid X-activated receptor Protein

Farnesoid X receptor (FXR), a NR1 Thyroid Hormone-Like Receptor, has been shown to affect bile-acid metabolism in the liver and intestine. FXR binds to target DNA as a heterodimer (with retinoid X receptors) and is activated by bile acids. Binding of bile acids to the RXR/FXR heterodimer in liver represses CYP7A1 expression and bile-acid production, leading to a failure to solubilize and absorb cholesterol.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
 

Requested From: 
Date Requested: 10/22/2017

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