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Human NR1H4 / FXR Recombinant (GST) Protein LS-G31879

Ordering

Wt. Vol. Conc. Price
10 µg - - $415
Inquire for larger quantities
LSBio (USA Sales Only) LSBio (USA Sales Only)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular NR1H4 / FXR Proteins

Human NR1H4 / FXR Recombinant (His + SUMO) Protein - LS-G21829
E. coli Expression System
His + SUMO
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human NR1H4 / FXR Recombinant (His + GST + S) Protein - LS-G24613
E. coli Expression System
His + GST + S
Unpurified
Rat NR1H4 / FXR Recombinant (His + GST) Protein - LS-G24614
E. coli Expression System
His + GST
Unpurified

100% Guaranteed 100% Guaranteed
LS-G31879
Recombinant Protein
NR1H4 / FXR
Human
78.8 kDa
MGSKMNLIEH SHLPTTDEFS FSENLFGVLT EQVAGPLGQN
LEVEPYSQYS NVQFPQVQPQ ISSSSYYSNL GFYPQQPEEW
YSPGIYELRR MPAETLYQGE TEVAEMPVTK KPRMGASAGR
IKGDELCVVC GDRASGYHYN ALTCEGCKGF FRRSITKNAV
YKCKNGGNCV MDMYMRRKCQ ECRLRKCKEM GMLAECMYTG
LLTEIQCKSK RLRKNVKQHA DQTVNEDSEG RDLRQVTSTT
KSCREKTELT PDQQTLLHFI MDSYNKQRMP QEITNKILKE
EFSAEENFLI LTEMATNHVQ VLVEFTKKLP GFQTLDHEDQ
IALLKGSAVE AMFLRSAEIF NKKLPSGHSD LLEERIRNSG
ISDEYITPMF SFYKSIGELK MTQEEYALLT AIVILSPDRQ
YIKDREAVEK LQEPLLDVLQ KLCKIHQPEN PQHFACLLGR
LTELRTFNHH HAEMLMSWRV NDHKFTPLLC EIWDVQ
Wheat Germ Extract
Wheat
GST
Glutathione Sepharose
50 mM Tris-HCl, pH 8.0, 10 mM reduced glutathione
Store at -80°C. Avoid freeze-thaw cycles.
For research use only.

About NR1H4 / FXR

Q96RI1 NM_005123 NP_005114.1

NR1H4 Protein, BAR Protein, Farnesyl x receptor Protein, FXR Protein, HRR1 Protein, Farnesoid x activated receptor Protein, Farnesoid X receptor Protein, Farnesol receptor HRR-1 Protein, HRR-1 Protein, RXR-interacting protein 14 Protein, RIP14 Protein, Bile acid receptor Protein, Farnesoid X nuclear receptor Protein, Farnesoid X-activated receptor Protein

Farnesoid X receptor (FXR), a NR1 Thyroid Hormone-Like Receptor, has been shown to affect bile-acid metabolism in the liver and intestine. FXR binds to target DNA as a heterodimer (with retinoid X receptors) and is activated by bile acids. Binding of bile acids to the RXR/FXR heterodimer in liver represses CYP7A1 expression and bile-acid production, leading to a failure to solubilize and absorb cholesterol.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
12.5% SDS-PAGE of human NR1H4 stained with Coomassie Blue
 

Requested From: United States
Date Requested: 12/10/2016

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