Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
NDRG2 Human Recombinant produced in E. coli is a single polypeptide chain containing 381 amino acids (1-357) and having a molecular mass of 41.8 kDa.NDRG2 is fused to a 24 amino acid His-tag at N-terminus and purified by proprietary chromatographic techniques.
Greater than 90% by SDS-PAGE
20 mM Tris-HCl, pH 8.0, 20 mM NaCl, 20 mM Urea, 10% glycerol.
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
NDRG2 Protein, KIAA1248 Protein, N-myc downstream regulator 2 Protein, NDRG family member 2 Protein, SYLD Protein, NDR1-related protein NDR2 Protein, Protein Syld709613 Protein, Syld709613 protein Protein, Cytoplasmic protein Ndr1 Protein, Protein NDRG2 Protein
Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation.