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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
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Human MMP3 Protein (Recombinant 6His,C-terminus) (Tyr18-Cys477) - LS-G38898
Recombinant Human Matrix Metalloproteinase-3 is produced by our Mammalian expression system and the target gene encoding Tyr18-Cys477 is expressed with a 6His tag at the C-terminus.
Tyr18-Cys477
YPLDGAARGE
DTSMNLVQKY
LENYYDLEKD
VKQFVRRKDS
GPVVKKIREM
QKFLGLEVTG
KLDSDTLEVM
RKPRCGVPDV
GHFRTFPGIP
KWRKTHLTYR
IVNYTPDLPK
DAVDSAVEKA
LKVWEEVTPL
TFSRLYEGEA
DIMISFAVRE
HGDFYPFDGP
GNVLAHAYAP
GPGINGDAHF
DDDEQWTKDT
TGTNLFLVAA
HEIGHSLGLF
HSANTEALMY
PLYHSLTDLT
RFRLSQDDIN
GIQSLYGPPP
DSPETPLVPT
EPVPPEPGTP
ANCDPALSFD
AVSTLRGEIL
IFKDRHFWRK
SLRKLEPELH
LISSFWPSLP
SGVDAAYEVT
SKDLVFIFKG
NQFWAIRGNE
VRAGYPRGIH
TLGFPPTVRK
IDAAISDKEK
NKTYFFVEDK
YWRFDEKRNS
MEPGFPKQIA
EDFPGIDSKI
DAVFEEFGFF
YFFTGSSQLE
FDPNAKKVTH
TLKSNSWLNC
VDHHHHHH
Human Cells
Human
6His,C-terminus
Greater than 95% by SDS-PAGE
Not Tested
Less than 1.0 EU/µg protein (determined by LAL method).
Supplied as 0.2 µm filtered 20 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.05% Brij35, 10% Glycerol.
Store at less than -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.
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