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Catalog Number Size Price
LS-G48798-50 50 µg $364 
LS-G48798-1 1 mg $2,003 
LDLR / LDL Receptor Protein - Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized human PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.61 µg/ml.
LDLR / LDL Receptor Protein - Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized mouse PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.12 µg/ml.
LDLR / LDL Receptor Protein
LDLR / LDL Receptor Protein - Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized human PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.61 µg/ml.
LDLR / LDL Receptor Protein - Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized mouse PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.12 µg/ml.
LDLR / LDL Receptor Protein
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Human LDLR / LDL Receptor Protein (Recombinant His,C-terminus) (Met1-Arg788) - LS-G48798

Human LDLR / LDL Receptor Protein (Recombinant His,C-terminus) (Met1-Arg788) - LS-G48798

Description:
LDLR / LDL Receptor Protein LS-G48798 is a Recombinant Human LDLR / LDL Receptor produced in HEK 293 Cells Met1-Arg788 with His,C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Price
Catalog Number
$364
LS-G48798-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Description:
LDLR / LDL Receptor Protein LS-G48798 is a Recombinant Human LDLR / LDL Receptor produced in HEK 293 Cells Met1-Arg788 with His,C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only

Specifications

Type
Recombinant Protein
Target
LDLR / LDL Receptor
Synonyms
LDLR | FHC | LDL receptor | LDLCQ2
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Applications
  • Binding
  • ELISA
  • Functional Assay
  • Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Tag
His,C-terminus
Region
Met1-Arg788
Predicted Molecular Weight
The secreted recombinant human LDLR comprises 777 amino acids with a predicted molecular mass of 86 kDa. As a result of different glycosylation, it migarates with the apparent molecular mass of 110-140 kDa in SDS-PAGE under reducing conditions corresponding to the mature and immature form.
Expression System
HEK 293 Cells
Source Species
Human
Purification
> 85 % as determined by SDS-PAGE
Bio-Activity
Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized human PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.61 µg/ml. Immobilized mouse PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.12 µg/ml.
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from sterile PBS, pH 7.4, with 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Reconstitution
Please refer to included instructions for detailed information.
Storage
Aliquot and store at -20°C to -80°C for one year. Avoid repeated freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This protein carries the LSBio 100% Guarantee.
LSBio Guarantee
About LDLR / LDL Receptor
P01130 NM_000527 NP_000518.1

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Functional Assay

LDLR / LDL Receptor Protein - Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized human PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.61 µg/ml.
Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized human PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.61 µg/ml.

Functional Assay

LDLR / LDL Receptor Protein - Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized mouse PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.12 µg/ml.
Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized mouse PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.12 µg/ml.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

LDLR / LDL Receptor Protein

Functional Assay

LDLR / LDL Receptor Protein - Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized human PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.61 µg/ml.
Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized human PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.61 µg/ml.

Functional Assay

LDLR / LDL Receptor Protein - Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized mouse PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.12 µg/ml.
Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized mouse PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.12 µg/ml.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

LDLR / LDL Receptor Protein

Functional Assay

LDLR / LDL Receptor Protein - Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized human PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.61 µg/ml.
Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized human PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.61 µg/ml.

Functional Assay

LDLR / LDL Receptor Protein - Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized mouse PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.12 µg/ml.
Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized mouse PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.12 µg/ml.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

LDLR / LDL Receptor Protein

Functional Assay

LDLR / LDL Receptor Protein - Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized human PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.61 µg/ml.
Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized human PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.61 µg/ml.

Functional Assay

LDLR / LDL Receptor Protein - Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized mouse PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.12 µg/ml.
Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized mouse PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.12 µg/ml.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

LDLR / LDL Receptor Protein

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/17/2024