Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Recombinant KIR2DS4 produced in E.Coli is a single, non-glycosylated polypeptide chain containing amino acids 1-202 and having a molecular mass of 22.2 kDa. The KIR2DS4 is purified by proprietary chromatographic techniques.
aa 23-223 of P43632
Greater than 95% by SDS-PAGE and HPLC
20 mM Tris-HCl, pH 7.5.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
KIR2DS4 Protein, CD158I Protein, KIR antigen 2DS4 Protein, MHC class I NK cell receptor Protein, NKAT8 Protein, KKA3 Protein, NKAT-8 Protein, CD158i antigen Protein, Cl-39 Protein, KIR1D Protein, KIR412 Protein, p58 NK receptor CL-39/CL-17 Protein
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2).