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Human KEAP1 Recombinant (GST) Protein LS-G31817

Ordering

Wt. Vol. Conc. Price
10 µg - - $415
Inquire for larger quantities
LSBio (USA Sales Only) LSBio (USA Sales Only)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular KEAP1 Proteins

Human KEAP1 Recombinant (His + S) Protein - LS-G26132
E. coli Expression System
His + S
Unpurified
Mouse KEAP1 Recombinant (His + S) Protein - LS-G26133
E. coli Expression System
His + S
Unpurified
Baculovirus KEAP1 Protein - LS-G53344
None
Unpurified

100% Guaranteed 100% Guaranteed
LS-G31817
Recombinant Protein
KEAP1
Human
94.38 kDa
MQPDPRPSGA GACCRFLPLQ SQCPEGAGDA VMYASTECKA
EVTPSQHGNR TFSYTLEDHT KQAFGIMNEL RLSQQLCDVT
LQVKYQDAPA AQFMAHKVVL ASSSPVFKAM FTNGLREQGM
EVVSIEGIHP KVMERLIEFA YTASISMGEK CVLHVMNGAV
MYQIDSVVRA CSDFLVQQLD PSNAIGIANF AEQIGCVELH
QRAREYIYMH FGEVAKQEEF FNLSHCQLVT LISRDDLNVR
CESEVFHACI NWVKYDCEQR RFYVQALLRA VRCHSLTPNF
LQMQLQKCEI LQSDSRCKDY LVKIFEELTL HKPTQVMPCR
APKVGRLIYT AGGYFRQSLS YLEAYNPSDG TWLRLADLQV
PRSGLAGCVV GGLLYAVGGR NNSPDGNTDS SALDCYNPMT
NQWSPCAPMS VPRNRIGVGV IDGHIYAVGG SHGCIHHNSV
ERYEPERDEW HLVAPMLTRR IGVGVAVLNR LLYAVGGFDG
TNRLNSAECY YPERNEWRMI TAMNTIRSGA GVCVLHNCIY
AAGGYDGQDQ LNSVERYDVE TETWTFVAPM KHRRSALGIT
VHQGRIYVLG GYDGHTFLDS VECYDPDTDT WSEVTRMTSG
RSGVGVAVTM EPCRKQIDQQ NCTC
Wheat Germ Extract
Wheat
GST
Glutathione Sepharose
50 mM Tris-HCl, pH 8.0, 10 mM reduced glutathione
Store at -80°C. Avoid freeze-thaw cycles.
For research use only.

About KEAP1

Q14145 NM_012289 NP_036421.2

KEAP1 Protein, Cytosolic inhibitor of Nrf2 Protein, INrf2 Protein, KLHL19 Protein, Kelch-like protein 19 Protein, KIAA0132 Protein

Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
12.5% SDS-PAGE of human KEAP1 stained with Coomassie Blue
 

Requested From: United States
Date Requested: 12/5/2016

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