IL6R / IL6 Receptor Protein LS-G27205 is Recombinant Human IL6R / IL6 Receptor aa 20-365 of P08887 produced in Hamster-Chinese It is biologically active and is low in endotoxin Less than 0.2 EU/µg protein (determined by LAL method)..
IL6R / IL6 Receptor
Predicted Molecular Weight
54-56 kDa (SDS-PAGE)
Interleukin-6 Receptor Alpha, also known as IL-6RA, IL-6R1 and CD126, belongs to the type I cytokine receptor family. It is mainly expressed on T cells, fibroblasts and macrophages. IL-6RA couples with gp130 to form the IL-6 receptor; IL-6RA binds specifically to IL-6 and depends on gp130 to transmit signals. IL-6RA dysfunction has been correlated with the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Soluble IL-6RA, which consists of only the extracellular domain of IL-6RA, acts as an agonist of IL-6 activity.
aa 20-365 of P08887
Greater than 95% by SDS-PAGE and HPLC
ED50 < 0.2 µg/ml, measured in a cell proliferation assay using M1 cells in the presence of 10 ng/ml human IL-6.
Less than 0.2 EU/µg protein (determined by LAL method).
Lyophilized from PBS
ddH2O or PBS at 100 ug/ml
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
For research use only.
About IL6R / IL6 Receptor