Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Interleukin-37 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 167 amino acids (Lys27-Asp192) and having a molecular mass of 18.6kDa.The IL37 is purified by proprietary chromatographic techniques.
Greater than 95% by SDS-PAGE and HPLC
Lyophilized from 20 mM phosphate buffer, pH 7.4.
Store at -20°C lyophilized. Once reconstituted, aliquot to avoid freeze/thaw and store at -20°C.
IL37 Protein, FIL1 Protein, FIL1 zeta Protein, FIL1(ZETA) Protein, IL-1 zeta Protein, IL-1F7 Protein, IL-1H Protein, IL-1RP1 Protein, IL-1X Protein, IL-37 Protein, Interleukin-1 homolog 4 Protein, Interleukin-1 zeta Protein, Interleukin-1-related protein Protein, Interleukin-23 Protein, Interleukin-37 Protein, IL1F7 Protein, Interleukin 1, zeta Protein, Interleukin-1 family member 7 Protein, FIL1Z Protein, IL-1H4 Protein, IL1RP1 Protein, Interleukin 1 family member 7 Protein, Interleukin 37 Protein, IL-1X protein Protein, IL1H4 Protein, Interleukin-1 superfamily z Protein
IL37 is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.