Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Less than 1.0 EU/µg protein (determined by LAL method).
Lyophilized from 0.2 µm filtered 20 mM Tris-HCl, pH 7.5, 150 mM NaCl.
Lyophilized protein should be stored at less than -20°C. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at less than -20°C for 3 months.
IL36RN Protein, FIL1 Protein, FIL1D Protein, IL-1 delta Protein, IL-1 related protein 3 Protein, IL-1HY1 Protein, IL-1RP3 Protein, IL-1-related protein 3 Protein, IL1F5 Protein, IL1RP3 Protein, IL1L1 Protein, IL36RA Protein, Interleukin-1 delta Protein, Family of interleukin 1-delta Protein, FIL1 delta Protein, IL-1L1 Protein, IL-1ra homolog 1 Protein, Interleukin-1 family member 5 Protein, Interleukin-1-like protein 1 Protein, FIL1(DELTA) Protein, IL-1F5 Protein, IL1HY1 Protein, Interleukin-1 HY1 Protein, PSORP Protein
Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation.