Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
| Catalog Number | Size | Price |
|---|---|---|
| LS-G47878-100 | 100 µg | $570 |
Human IL2RB / CD122 Protein (Recombinant His,C-terminus) (Met1-Asp239) - LS-G47878
Human IL2RB / CD122 Protein (Recombinant His,C-terminus) (Met1-Asp239) - LS-G47878
Description:
IL2RB / CD122 Protein LS-G47878 is a Recombinant Human IL2RB / CD122 produced in HEK 293 Cells Met1-Asp239 with His,C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
IL2RB / CD122 Protein LS-G47878 is a Recombinant Human IL2RB / CD122 produced in HEK 293 Cells Met1-Asp239 with His,C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
IL2RB / CD122
Synonyms
IL2RB | CD122 | CD122 antigen | IL-2 receptor subunit beta | IL15RB | Interleukin 15 receptor, beta | p70-75 | IL-2R subunit beta | IL-2RB | Interleukin 2 receptor, beta
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Applications
- Binding
- ELISA
- Functional Assay
- Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Tag
His,C-terminus
Region
Met1-Asp239
Predicted Molecular Weight
The mature recombinant human IL2 Rß consists of 219 amino acids and has a predicted molecular mass of 25.2 kDa. As a result of glycosylation, the rh IL2 Rß migrates as an approximately 40 kDa protein in SDS-PAGE under reducing conditions.
Expression System
HEK 293 Cells
Source Species
Human
Purification
> 90 % as determined by SDS-PAGE
Bio-Activity
Measured by its binding ability in a functional ELISA. Immobilized human IL2Rb at 10 µg/ml (100 µl/well) can bind biotinylated human IL2, The EC50 of biotinylated human IL2 is 0.1-0.24 µg/mL. Measured by its ability to inhibit IL15-dependent proliferation of MO7e human megakaryocytic leukemic cells in the presence of 4.0 ng/mL of recombinant human IL-15. The ED50 for this effect is 1-4µg/mL.
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from sterile 100mM NaCl, 50mM Tris, pH 7.5, with 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Reconstitution
Please refer to included instructions for detailed information.
Storage
Aliquot and store at -20°C to -80°C for one year. Avoid repeated freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About IL2RB / CD122
Publications (0)
Customer Reviews (0)
Images
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Popular IL2RB / CD122 Proteins
Source:
E. coli
Tag:
6His, N-terminus
Source:
E. coli
Tag:
His, N-Terminal
Source:
Human
Tag:
6His, C-terminus
Source:
Human
Tag:
Fc, C-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/25/2024
Date Requested: 4/25/2024
