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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Human IL2 Protein (Recombinant) - LS-G23498

Catalog
Size
Price
LS-G23498-10
10 µg
$205
LS-G23498-50
50 µg
$285
LS-G23498-100
100 µg
$385
LS-G23498-500
500 µg
$465
LS-G23498-1
1 mg
$800
Description
IL2 Protein LS-G23498 is Recombinant Human IL2 in E. coli It is biologically active and is low in endotoxin Less than 1.0 EU/µg protein (determined by LAL method)..
Type
Animal-Free  Recombinant Protein
Target
IL2
Species
Human
Predicted Molecular Weight
15.5 kDa
Details
Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes.  IL-2 signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages. This product is produced with no animal or human origin raw products. All processing and handling employs animal free equipment and animal free protocols.
AA Sequence
MAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
Expression System
E. coli
Source Species
E. coli
Purification
Greater than 95% by SDS-PAGE
Bio-Activity
Tested using: CTLL-2 cell proliferation. Less than or equal to 3 ng/mL and greater than or equal to 3.3 x 10^5 units/mg. In addition to the acceptance criteria, this product has been tested with the following assay: Primary human T cell proliferation (typical ED50 is less than 1 ng/mL). The specific activity of Human IL-2 is approximately 1.8 x 10^4 IU/µg, which is calibrated against recombinant human IL-2 WHO International Standard (NIBSC code: 86/500).
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitution
Reconstitute in sterile 10 mM HCl at a concentration of 0.1 mg/ml.
Storage
Store at -20°C to -80°C for up to 1 year. Store at 4°C for up to 1 month or up to 3 months at -20°C to -80°C after reconstitution.
Restrictions
For research use only.
About IL2
P60568 NM_000586 NP_000577.2

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Images

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Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

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Requested From: United States
Date Requested: 7/22/2019
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