IL11 Protein LS-G23660 is Recombinant Human IL11 in E. coli It is biologically active and is low in endotoxin Less than 1.0 EU/µg protein (determined by LAL method)..
Predicted Molecular Weight
Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Ralpha (IL-11Ra) receptor to activate JAK downstream signaling. Human IL-11 shows activity on murine cells.
Greater than 95% by SDS-PAGE
Tested using: T11 cell proliferation OR. TF-1 cell proliferation. Less than or equal to 2.5 ng/mL and greater than or equal to 4.0 x 10^5 units/mg OR. Less than or equal to 10 ng/mL and greater than or equal to 1.0 x 10^5 units/mg.
Less than 1.0 EU/µg protein (determined by LAL method).
Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitute in sterile water to 0.1 mg/ml
Store at -20°C to -80°C for up to 1 year. Store at 4°C for up to 1 month or up to 3 months at -20°C to -80°C after reconstitution.
For research use only.