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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Human IFN Gamma / Interferon Gamma Protein (Recombinant) - LS-G23652

Catalog
Size
Price
LS-G23652-20
20 µg
$205
LS-G23652-100
100 µg
$285
LS-G23652-250
250 µg
$445
LS-G23652-500
500 µg
$710
LS-G23652-1
1 mg
$1,230
Description
IFN Gamma / Interferon Gamma Protein LS-G23652 is Recombinant Human IFN Gamma / Interferon Gamma in E. coli It is biologically active and is low in endotoxin Less than 1.0 EU/µg protein (determined by LAL method)..
Type
Animal-Free  Recombinant Protein
Target
IFN Gamma / Interferon Gamma
Species
Human
Predicted Molecular Weight
16.9 kDa
Details
Interferon gamma (IFN?) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN? is produced by T cells and natural killer cells following antigen-specific activation. IFN? binds IFN? receptors (IFN?R1 and IFN?R2), which are expressed on most immune cells, to activate the JAK-STAT pathway. IFN?-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules. Human IFN? is not cross-reactive with mouse IFN?. This product is produced with no animal or human origin raw products. All processing and handling employs animal free equipment and animal free protocols.
AA Sequence
MQDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQMLFQGRRASQ
Expression System
E. coli
Source Species
E. coli
Purification
Greater than 95% by SDS-PAGE
Bio-Activity
Tested using: Viral CPE assay using EMC virus on A549 cells. and greater than or equal to 1.0 x 10^7 units/mg.
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from a sterile filtered solution 10 mM sodium phosphate, pH 7.5, 50 mM sodium chloride
Reconstitution
Reconstitute in sterile water to 0.1 mg/ml
Storage
Store at -20°C to -80°C for up to 1 year. Store at 4°C for up to 1 month or up to 3 months at -20°C to -80°C after reconstitution.
Usage Summary
If a precipitate is observed, centrifuge the solution thoroughly and use only the soluble fraction (removing it from the precipitate). A 10% overfill has been added to compensate for any loss of protein in the precipitate.
Restrictions
For research use only.
About IFN Gamma / Interferon Gamma
P01579 NM_000619 NP_000610.2

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Requested From: United States
Date Requested: 6/25/2019
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