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Human ICOS / CD278 Recombinant (Human mutant IgG1 Fc) Protein LS-G4091


Wt. Vol. Conc. Price
25 µg - - $265
100 µg - - $385
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)

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Recombinant Protein
ICOS / CD278
The extracellular domain of human CD278 [ICOS] (aa 21-139) is fused to the N-terminus of the Fc region of a mutant human IgG1.
aa 21-139
CHO Cells
Human mutant IgG1 Fc
Greater than 98% by SDS-PAGE
Shows the biological function of the CD278 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
Less than 0.06 EU/µg protein (determined by LAL method).
Lyophilized from PBS.
Store lyophilized at -20°C for at least 1 year. Once reconstituted store at +4°C for immediate use, or aliquot and store at -20°C for up to 3 months. Avoid repeat freeze-thaw cycles.
For research use only.

About ICOS / CD278

Q9Y6W8 AJ277832 CAC06612.1

ICOS Protein, AILIM Protein, CD278 Protein, CVID1 Protein, Inducible costimulator Protein, Inducible T-cell co-stimulator Protein, CD278 antigen Protein, Inducible T-cell costimulator Protein

Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10.

Requested From: United States
Date Requested: 10/28/2016

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