Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
| Catalog Number | Size | Price |
|---|---|---|
| LS-G48008-50 | 50 µg | $410 |
| LS-G48008-500 | 500 µg | $1,428 |
Human HMG1 / HMGB1 Protein (Recombinant Human IgG1 Fc, N-terminus) (Met1-Glu215) - LS-G48008
Human HMG1 / HMGB1 Protein (Recombinant Human IgG1 Fc, N-terminus) (Met1-Glu215) - LS-G48008
Description:
HMG1 / HMGB1 Protein LS-G48008 is a Recombinant Human HMG1 / HMGB1 produced in HEK 293 Cells Met1-Glu215 with Human IgG1 Fc, N-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
HMG1 / HMGB1 Protein LS-G48008 is a Recombinant Human HMG1 / HMGB1 produced in HEK 293 Cells Met1-Glu215 with Human IgG1 Fc, N-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
HMG1 / HMGB1
Synonyms
HMGB1 | Amphoterin | High mobility group protein B1 | High mobility group box 1 | High mobility group protein 1 | HMG1 | HMG3 | SBP-1 | High-mobility group box 1 | HMG-1
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Applications
- Binding
- ELISA
- Functional Assay
- Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Tag
Human IgG1 Fc, N-terminus
Region
Met1-Glu215
Predicted Molecular Weight
The recombinant human HMGB1/Fc is a disulfide-linked homodimeric protein.The reduced monomer consists of 452 amino acids and has a predictedmolecular mass of 51.5 kDa. As a result of glycosylation, the apparent molecular mass of rhHMGB1/Fc monomer is approximately 55-60 kDa inSDS-PAGE under reducing conditions.
Expression System
HEK 293 Cells
Source Species
Human
Purification
> 97 % as determined by SDS-PAGE
Bio-Activity
Measured by its binding ability in a functional ELISA. Immobilized recombinant mouse AGER at 2 µg/ml (100 µl/well) can bind human HMGB1. The EC50 of human HMGB1 is 0.23 µg/ml.
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5, with 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Reconstitution
Please refer to included instructions for detailed information.
Storage
Aliquot and store at -20°C to -80°C for one year. Avoid repeated freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About HMG1 / HMGB1
Publications (0)
Customer Reviews (0)
Images
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Popular HMG1 / HMGB1 Proteins
Source:
E. coli
Tag:
His, N-Terminal
Source:
E. coli
Tag:
His, N-Terminal
Source:
Hamster-Chinese
Tag:
Human IgG1 Fc
Source:
E. coli
Tag:
6His, C-terminus
Source:
Human
Tag:
His,C-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/19/2024
Date Requested: 4/19/2024
