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Human HMBS / PBGD Recombinant (6His,C-terminus) Protein (Ser2-His361) - LS-G39253

Ordering

Wt. Vol. Conc. Price
10 µg - - Unavailable
50 µg - - Unavailable
500 µg - - Unavailable
1000 µg - - Unavailable

Most Popular HMBS / PBGD Proteins

Human HMBS / PBGD Recombinant (His) Protein - LS-G1687
E. coli Expression System
385 AA
His
Purified
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human HMBS / PBGD Recombinant (His) Protein - LS-G17800
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Human HMBS / PBGD Recombinant (His + T7) Protein - LS-G25496
E. coli Expression System
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Lyophilized
Human HMBS / PBGD Recombinant (GST) Protein - LS-G28849
Wheat Wheat Germ Extract
361 AA
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Purified
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human HMBS / PBGD Recombinant (6His,C-terminus) Protein (Ser2-His361) - LS-G39253
Human Human Cells
368 AA
6His,C-terminus
Purified / Lyophilized / Endotoxin Level: Less than 0.1 EU/µg protein (determined by LAL method).

100% Guaranteed 100% Guaranteed
LS-G39253
Recombinant Protein
HMBS / PBGD
Human
40.5kD
Recombinant Human Porphobilinogen Deaminase is produced by our Mammalian expression system and the target gene encoding Ser2-His361 is expressed with a 6His tag at the C-terminus.
Ser2-His361
SGNGNAAATA EENSPKMRVI RVGTRKSQLA RIQTDSVVAT
LKASYPGLQF EIIAMSTTGD KILDTALSKI GEKSLFTKEL
EHALEKNEVD LVVHSLKDLP TVLPPGFTIG AICKRENPHD
AVVFHPKFVG KTLETLPEKS VVGTSSLRRA AQLQRKFPHL
EFRSIRGNLN TRLRKLDEQQ EFSAIILATA GLQRMGWHNR
VGQILHPEEC MYAVGQGALG VEVRAKDQDI LDLVGVLHDP
ETLLRCIAER AFLRHLEGGC SVPVAVHTAM KDGQLYLTGG
VWSLDGSDSI QETMQATIHV PAQHEDGPED DPQLVGITAR
NIPRGPQLAA QNLGISLANL LLSKGAKNIL DVARQLNDAH
VDHHHHHH
Human Cells
Human
6His,C-terminus
Greater than 95% by SDS-PAGE
Less than 0.1 EU/µg protein (determined by LAL method).
Lyophilized
Lyophilized protein should be stored at < -20°C. Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
For research use only.

About HMBS / PBGD

P08397 NM_000190 NP_000181.2

HMBS Protein, Hydroxymethylbilane synthase Protein, PBG-D Protein, PBGD Protein, PORC Protein, Porphyria, acute Chester type Protein, Porphobilinogen deaminase Protein, Pre-uroporphyrinogen synthase Protein, UPS Protein, Uroporphyrinogen I synthetase Protein, Uroporphyrinogen I synthase Protein

HMBS / PBGD is a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

Requested From: 
Date Requested: 4/25/2017

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