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Human HMBS / PBGD Recombinant (6His,C-terminus) Protein LS-G39253

Ordering

Wt. Vol. Conc. Price
- 10 µl - $265
- 50 µl - $465
- 500 µl - $1,605
- 1000 µl - $2,310
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular HMBS / PBGD Proteins

Human HMBS / PBGD Recombinant (His) Protein - LS-G1687
E. coli Expression System
His
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human HMBS / PBGD Recombinant (His) Protein - LS-G17800
E. coli Expression System
His
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Human HMBS / PBGD Recombinant (6His,C-terminus) Protein - LS-G39253
Human Human Cells
6His,C-terminus
Unpurified

100% Guaranteed 100% Guaranteed
LS-G39253
Recombinant Protein
HMBS / PBGD
Human
Recombinant Human Porphobilinogen Deaminase is produced by our Mammalian expression system and the target gene encoding Ser2-His361 is expressed with a 6His tag at the C-terminus.
Ser2-His361
SGNGNAAATA EENSPKMRVI RVGTRKSQLA RIQTDSVVAT
LKASYPGLQF EIIAMSTTGD KILDTALSKI GEKSLFTKEL
EHALEKNEVD LVVHSLKDLP TVLPPGFTIG AICKRENPHD
AVVFHPKFVG KTLETLPEKS VVGTSSLRRA AQLQRKFPHL
EFRSIRGNLN TRLRKLDEQQ EFSAIILATA GLQRMGWHNR
VGQILHPEEC MYAVGQGALG VEVRAKDQDI LDLVGVLHDP
ETLLRCIAER AFLRHLEGGC SVPVAVHTAM KDGQLYLTGG
VWSLDGSDSI QETMQATIHV PAQHEDGPED DPQLVGITAR
NIPRGPQLAA QNLGISLANL LLSKGAKNIL DVARQLNDAH
VDHHHHHH
Human Cells
Human
6His,C-terminus
Lyophilized
For research use only.

About HMBS / PBGD

P08397 NM_000190 NP_000181.2

HMBS Protein, Hydroxymethylbilane synthase Protein, PBG-D Protein, PBGD Protein, PORC Protein, Porphyria, acute Chester type Protein, Porphobilinogen deaminase Protein, Pre-uroporphyrinogen synthase Protein, UPS Protein, Uroporphyrinogen I synthetase Protein, Uroporphyrinogen I synthase Protein

HMBS / PBGD is a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

Requested From: United States
Date Requested: 12/8/2016

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