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Catalog Number Size Price
LS-G48347-50 50 µg $441 
GZMB / Granzyme B Protein

Human GZMB / Granzyme B Protein (Recombinant His,C-terminus) (Met1-Tyr247) - LS-G48347

Human GZMB / Granzyme B Protein (Recombinant His,C-terminus) (Met1-Tyr247) - LS-G48347

Description:
GZMB / Granzyme B Protein LS-G48347 is a Recombinant Human GZMB / Granzyme B produced in HEK 293 Cells Met1-Tyr247 with His,C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Price
Catalog Number
$441
LS-G48347-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Description:
GZMB / Granzyme B Protein LS-G48347 is a Recombinant Human GZMB / Granzyme B produced in HEK 293 Cells Met1-Tyr247 with His,C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only

Specifications

Type
Recombinant Protein
Target
GZMB / Granzyme B
Synonyms
GZMB | CCPI | CGL-1 | Cathepsin G-like 1 | CSP-B | CTLA-1 | CTLA1 | CGL1 | CSPB | Fragmentin 2 | GRB | HLP | Human lymphocyte protein | Fragmentin-2 | SECT | Lymphocyte protease | T-cell serine protease 1-3E | C11 | CTSGL1 | Cytotoxic serine protease B | Granzyme B | Granzyme-2
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Applications
  • Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Tag
His,C-terminus
Region
Met1-Tyr247
Predicted Molecular Weight
The recombinant human Granzyme B consists of 240 amino acids and has a calculated molecular mass of 27 kDa. As a result of glycosylation, the apparent molecular mass of rhGranzyme B is approximately 36 kDa in SDS-PAGE under reducing conditions.
Expression System
HEK 293 Cells
Source Species
Human
Purification
> 97 % as determined by SDS-PAGE
Bio-Activity
Measured by its ability to cleave a peptide substrate, tButyloxycaronylAlaAlaAspThioBenzylester (BocAADSBzl),in the presence of 5,5’Dithiobis (2nitrobenzoic acid) (DTNB). The specific activity is >1500 pmol/min/µg.
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from sterile PBS, pH 7.4, with 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Reconstitution
Please refer to included instructions for detailed information.
Storage
Aliquot and store at -20°C to -80°C for one year. Avoid repeated freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This protein carries the LSBio 100% Guarantee.
LSBio Guarantee
About GZMB / Granzyme B
P10144 NM_004131 NP_004122.2

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Images

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

GZMB / Granzyme B Protein

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

GZMB / Granzyme B Protein

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

GZMB / Granzyme B Protein

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

GZMB / Granzyme B Protein

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/19/2024