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Human GREM1 / Gremlin-1 Recombinant Protein LS-G107

Ordering

Wt. Vol. Conc. Price
10 µg - - $215
50 µg - - $285
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular GREM1 / Gremlin-1 Proteins

Human GREM1 / Gremlin-1 Recombinant (His) Protein - LS-G2176
E. coli Expression System
His
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human GREM1 / Gremlin-1 Recombinant Protein - LS-G4947
Hamster-Chinese CHO Cells
None
Unpurified / Endotoxin Level: Less than 0.1 ng/µg of protein (less than 1EU/µg).
Human GREM1 / Gremlin-1 Recombinant (His) Protein - LS-G19035
E. coli Expression System
His
Unpurified / Lyophilized

100% Guaranteed 100% Guaranteed
LS-G107
Recombinant Protein
GREM1 / Gremlin-1
Human
18.3 kDa
KKKGSQGAIP PPDKAQHNDS EQTQSPQQPG SRNRGRGQGR
GTAMPGEEVL ESSQEALHVT ERKYLKRDWC KTQPLKQTIH
EEGCNSRTII NRFCYGQCNS FYIPRHIRKE EGSFQSCSFC
KPKKFTTMMV TLNCPELQPP TKKKRVTRVK QCRCISIDLD
CHO Cells
Hamster-Chinese
None
Greater than 90% by SDS-PAGE and HPLC
Determined by its ability to inhibit BMP-4 induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 0.07-0.11 ug/ml.
Less than 0.1 ng/µg of protein (less than 1EU/µg).
Sterile filtered, lyophilized from 10 mM sodium phosphate, pH 7.5, 150 mM sodium chloride
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
If lyophilized, can be stored for 1 month at room temperature, 6 months at 4°C, or through the expiration date at -20°C to -80°C. Once reconstituted per the supplied instructions, can be stored for 3 months at -20°C to -80°C, or for 1 week at 2°C to 8°C. Avoid repeat freeze-thaw cycles.
For research use only.

About GREM1 / Gremlin-1

O60565 NM_013372 NP_037504.1

GREM1 Protein, CKTSF1B1 Protein, DAN domain family member 2 Protein, DAND2 Protein, DRM Protein, GREMLIN Protein, Gremlin 1-like protein Protein, Increased in high glucose-2 Protein, Gremlin-1 Protein, PIG2 Protein, Proliferation-inducing gene 2 Protein, Gremlin 1 Protein, IHG-2 Protein

GREM1 / Gremlin-1 is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins.

Requested From: United States
Date Requested: 12/5/2016

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