Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human GRAP2 / GRID Protein (Recombinant His) - LS-G18625
E. coli Expression System
GRAP2 / GRID
GRAP2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 350 amino acids (1-330.a.a) and having a molecular mass of 40.0kDa. GRAP2 is fused to a 20 amino acid His-tag at N-terminus and purified by proprietary chromatographic techniques.
Greater than 90% by SDS-PAGE
20 mM Tris-HCl, pH 8.0, 0.2 M NaCl, 0.2 M DTT, 0.2 M EDTA, 30% glycerol.
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
GRAP2 Protein, Adapter protein GRID Protein, GRAP-2 Protein, GRB2L Protein, Grf40 adapter protein Protein, GRB2-related adapter protein 2 Protein, GRBLG Protein, Grf-40 Protein, Grf40 Protein, GRB2-related adaptor protein 2 Protein, GRID Protein, MONA Protein, Protein GADS Protein, SH3-SH2-SH3 adaptor molecule Protein, SH3-SH2-SH3 adapter Mona Protein, GADS Protein, GRB-2-like protein Protein, GrbX Protein, GRPL Protein, p38 Protein
GRAP2 / GRID is a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains.