Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is <10 ng/ml, corresponding to a specific activity of >1 x 105units/mg.
Less than 0.1 ng/µg of protein.
Lyophilized from 10 mM Tris, pH 7.6, 0.1 M NaCl
Reconstitute in 10 mM Tris, pH 7.6, to 0.1-1.0 mg/ml. This solution can be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use. Repeated freeze/thaw cycles will result in some loss of activity.
FGF1 / Acidic FGF is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor.