Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
FERMT1 Protein, C20orf42 Protein, DTGCU2 Protein, Fermitin family homolog 1 Protein, Kindlin syndrome protein Protein, KIND1 Protein, Kindlin 1 Protein, UNC112A Protein, URP1 Protein, UNC112 related protein 1 Protein, Fermitin family member 1 Protein, Kindlerin Protein, Kindlin Protein, Kindlin-1 Protein, Unc-112-related protein 1 Protein
Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.