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Human Endostatin Recombinant (His) Protein LS-G19651


Wt. Vol. Conc. Price
20 µg - - $195
100 µg - - $255
1 mg - - $1,035
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)

Most Popular Endostatin Proteins

Human Endostatin Recombinant Protein - LS-G4561
E. coli Expression System
Unpurified / Endotoxin Level: Less than 0.1 ng/µg of protein.
Human Endostatin Recombinant Protein - LS-G4574
Pichia pastoris Yeast
Unpurified / Lyophilized / Endotoxin Level: Less than 0.1 ng/µg of protein.
Human Endostatin Recombinant (GST) Protein - LS-G22581
E. coli Expression System
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

100% Guaranteed 100% Guaranteed
Recombinant Protein
20.0 kDa
Endostatin Human Recombinant produced in Pichia Pastoris is a single, non-glycosylated, polypeptide having a total molecular mass of 20,000 Dalton C-terminal fragment of collagen XVIII that has been shown to act as a potent inhibitor of angiogenesis and tumor growth in vitro and in vivo. Induces tyrosine phosphorylation of Shc (SH2 domain adapter protein) leading to specific inhibition in endothelial cell prolifiration.The Endostatin is fused to His tag at N-terminus and purified by proprietary chromatographic techniques.
Pichia pastoris
Greater than 98% by SDS-PAGE and HPLC
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About Endostatin

P39060 NM_030582 NP_085059.2

COL18A1 Protein, Collagen, type XVIII, alpha 1 Protein, Collagen alpha-1(XVIII) chain Protein, Endostatin Protein, KNO Protein, KNO1 Protein, KS Protein, Multi-functional protein MFP Protein, Antiangiogenic agent Protein, Collagen alpha 1(xviii) Protein, Knobloch syndrome, type 1 Protein

Endostatin is the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors.

Requested From: United States
Date Requested: 10/21/2016

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