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Human DKK1 Recombinant Protein LS-G44953

Ordering

Wt. Vol. Conc. Price
2 µg - - $375
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular DKK1 Proteins

Human DKK1 Recombinant (His) Protein - LS-G19257
E. coli Expression System
His
Unpurified / Lyophilized
DKK1 Recombinant Protein - LS-G27007
Hamster-Chinese CHO Cells
None
Unpurified / Endotoxin Level: Less than 0.2 EU/µg protein (determined by LAL method).
Human DKK1 Recombinant Protein - LS-G27268
Hamster-Chinese CHO Cells
None
Unpurified / Endotoxin Level: Less than 0.2 EU/µg protein (determined by LAL method).

100% Guaranteed 100% Guaranteed
LS-G44953
Recombinant Protein
DKK1
Human
ADPTLNSVLN SNAIKNLPPP LGGAAGHPGS AVSAAPGILY
PGGNKYQTID NYQPYPCAED EECGTDEYCA SPTRGGDAGV
QICLACRKRR KRCMRHAMCC PGNYCKNGIC VSSDQNHFRG
EIEETITESF GNDHSTLDGY SRRTTLSSKM YHTKGQEGSV
CLRSSDCASG LCCARHFWSK ICKPVLKEGQ VCTKHRRKGS
HGLEIFQRCY CGEGLSCRIQ KDHHQASNSS RL
Baculovirus
None
Greater than 85% by SDS-PAGE
PBS, pH 7.4, 10% glycerol
For research use only.

About DKK1

O94907 NM_012242 NP_036374.1

DKK1 Protein, Dickkopf-1 like Protein, DKK-1 Protein, Dickkopf-1 Protein, Dickkopf-related protein 1 Protein, Dickkopf related protein-1 Protein, HDkk-1 Protein, Hdkk1 Protein, Dickkopf-like protein 1 Protein, SK Protein

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Requested From: United States
Date Requested: 12/9/2016

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