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Human CDK4 Recombinant (GST) Protein LS-G27866

Ordering

Wt. Vol. Conc. Price
10 µg - - $415
Inquire for larger quantities
LSBio (USA Sales Only) LSBio (USA Sales Only)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CDK4 Proteins

Human CDK4 Recombinant (His) Protein - LS-G18505
E. coli Expression System
His
Unpurified / Lyophilized
Human CDK4 Recombinant (6His + T7,N-terminus) Protein - LS-G39631
E. coli Expression System
6His + T7,N-terminus
Unpurified
CDK4 Recombinant Protein - LS-G41413
E. coli
None
Unpurified / Lyophilized

100% Guaranteed 100% Guaranteed
LS-G27866
Recombinant Protein
CDK4
Human
59.07 kDa
MATSRYEPVA EIGVGAYGTV YKARDPHSGH FVALKSVRVP
NGGGGGGGLP ISTVREVALL RRLEAFEHPN VVRLMDVCAT
SRTDREIKVT LVFEHVDQDL RTYLDKAPPP GLPAETIKDL
MRQFLRGLDF LHANCIVHRD LKPENILVTS GGTVKLADFG
LARIYSYQMA LTPVVVTLWY RAPEVLLQST YATPVDMWSV
GCIFAEMFRR KPLFCGNSEA DQLGKIFDLI GLPPEDDWPR
DVSLPRGAFP PRGPRPVQSV VPEMEESGAQ LLLEMLTFNP
HKRISAFRAL QHSYLHKDEG NPE
Wheat Germ Extract
Wheat
GST
Glutathione Sepharose
50 mM Tris-HCl, pH 8.0, 10 mM reduced glutathione
Store at -80°C. Avoid freeze-thaw cycles.
For research use only.

About CDK4

P11802 NM_000075 NP_000066.1

CDK4 Protein, Cell division protein kinase 4 Protein, Crk3 Protein, Cyclin-dependent kinase 4 Protein, CMM3 Protein, p34/cdk4 Protein, PSK-J3 Protein

Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
12.5% SDS-PAGE of human CDK4 stained with Coomassie Blue
 

Requested From: United States
Date Requested: 12/4/2016

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