Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human CDC73 / Parafibromin Protein (Recombinant 6His,N-terminus) (Met1-Glu260) - LS-G39573
E. coli Expression System
Purified / Lyophilized / Endotoxin Level: Less than 1.0 EU/µg protein (determined by LAL method).
CDC73 / Parafibromin
Recombinant Human CDC73 is produced by our E. coli expression system and the target gene encoding Met1-Glu260 is expressed with a 6His tag at the N-terminus.
Greater than 95% by SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
Lyophilized from 0.2 µm filtered 20 mM PB, pH 7.4, 150 mM NaCl.
Lyophilized protein should be stored at less than -20°C. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at less than -20°C for 3 months.
CDC73 Protein, C1orf28 Protein, Hyperparathyroidism 2 protein Protein, HPTJT Protein, HRPT2 Protein, Parafibromin Protein, HYX Protein
Tumor suppressor probably involved in transcriptional and post-transcriptional control pathways. May be involved in cell cycle progression through the regulation of cyclin D1/PRAD1 expression. Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency.