Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 1.0 EU/µg protein (determined by LAL method).
Greater than 90% by SDS-PAGE
20 mM Tris-HCl, pH 8.0, 0.4 M urea, 10% glycerol
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. Further dilutions can be made in assay buffer
CD200, also known as OX-2, is a type I membrane protein belonging to the Ig superfamily. It has a 202 amino acid extracellular domain and a short cytoplasmic domain. CD200 is widely expressed by a variety of cell types. It interacts with CD200R another Ig superfamily inhibitory receptor primarily expresses on leukocytes of the myeloid lineage to inhibit myeloid functions. It has been shown to be up regulated in CLL.