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Human CBLC Recombinant (GST) Protein LS-G32925

Ordering

Wt. Vol. Conc. Price
10 µg - - $415
Inquire for larger quantities
LSBio (USA Sales Only) LSBio (USA Sales Only)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CBLC Proteins

Human CBLC Recombinant (GST) Protein - LS-G32925
Wheat Wheat Germ Extract
GST
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Baculovirus CBLC Protein - LS-G50609
None
Unpurified
Baculovirus CBLC Protein - LS-G52521
None
Unpurified

100% Guaranteed 100% Guaranteed
LS-G32925
Recombinant Protein
CBLC
Human
77.88 kDa
MALAVAPWGR QWEEARALGR AVRMLQRLEE QCVDPRLSVS
PPSLRDLLPR TAQLLREVAH SRRAAGGGGP GGPGGSGDFL
LIYLANLEAK SRQVAALLPP RGRRSANDEL FRAGSRLRRQ
LAKLAIIFSH MHAELHALFP GGKYCGHMYQ LTKAPAHTFW
RESCGARCVL PWAEFESLLG TCHPVEPGCT ALALRTTIDL
TCSGHVSIFE FDVFTRLFQP WPTLLKNWQL LAVNHPGYMA
FLTYDEVQER LQACRDKPGS YIFRPSCTRL GQWAIGYVSS
DGSILQTIPA NKPLSQVLLE GQKDGFYLYP DGKTHNPDLT
ELGQAEPQQR IHVSEEQLQL YWAMDSTFEL CKICAESNKD
VKIEPCGHLL CSCCLAAWQH SDSQTCPFCR CEIKGWEAVS
IYQFHGQATA EDPGNSSDQE GRELELGQVP LSAPPLPPRP
DLPPRKPRNA QPKVRLLKGN SPPAALGPQD PAPA
Wheat Germ Extract
Wheat
GST
Glutathione Sepharose
50 mM Tris-HCl, pH 8.0, 10 mM reduced glutathione
Store at -80°C. Avoid freeze-thaw cycles.
For research use only.

About CBLC

Q9ULV8 NM_012116 NP_036248.3

CBLC Protein, CBL-3 Protein, CBL3 Protein, RNF57 Protein, SH3-binding protein CBL-C Protein, SH3-binding protein CBL-3 Protein, CBL-c Protein, CBL-SL Protein, RING finger protein 57 Protein

Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Functionally coupled with the E2 ubiquitin-protein ligases UB2D1, UB2D2 and UB2D3. Regulator of EGFR mediated signal transduction; upon EGF activation, ubiquitinates EGFR. Isoform 1, but not isoform 2, inhibits EGF stimulated MAPK1 activation. Promotes ubiquitination of SRC phosphorylated at 'Tyr-419'.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
12.5% SDS-PAGE of human CBLC stained with Coomassie Blue
 

Requested From: United States
Date Requested: 12/5/2016

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