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Human CASP8 / Caspase 8 Protein (Recombinant His + T7) (aa217-384) - LS-G12988

Catalog Size Price
LS-G12988-10 10 µg Unavailable
LS-G12988-50 50 µg Unavailable
LS-G12988-100 100 µg Unavailable
LS-G12988-200 200 µg Unavailable

Most Popular CASP8 / Caspase 8 Proteins

Human CASP8 / Caspase 8 Protein (Recombinant 6His,N-terminus) (aa215-478) - LS-G4183
E. coli Expression System
Purified / Lyophilized / Biologically Active
Mouse CASP8 / Caspase 8 Protein (Recombinant 6His,N-terminus) - LS-G4197
E. coli Expression System
Purified / Lyophilized / Biologically Active
Bovine CASP8 / Caspase 8 Protein (Recombinant His) (aa25-175) - LS-G12987
E. coli Expression System
Purified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Rat CASP8 / Caspase 8 Protein (Recombinant His + T7) (aa8-197) - LS-G24142
E. coli Expression System
His + T7
Mouse CASP8 / Caspase 8 Protein (Over-Expression Cell Culture Supernatant 6His,N-terminus) (Ser219-Pro480) - LS-G26822
Human HEK 293 Cells

100% Guaranteed
Recombinant Protein
CASP8 / Caspase 8
22.9 kDa
aa 217-384
E. coli
E. coli
His + T7
Greater than 95%
Not Tested
Not Tested
Lyophilized from PBS, pH 7.4, 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose, Proclin300.
Reconstitute in sterile PBS, pH 7.2-7.4.
Store at 4°C for up to 1 month, or aliquot and store at -80°C for up to 1 year. Avoid freeze-thaw cycles.
For research use only.

About CASP8 / Caspase 8

Q14790 nm_001228 AAC50645.1

CASP8 Protein, ALPS2B Protein, Apoptotic protease Mch-5 Protein, Apoptotic cysteine protease Protein, Casp-8 Protein, Caspase-8 Protein, CAP4 Protein, Caspase 8 Protein, MACH Protein, MCH5 Protein, MORT1-associated ced-3 homolog Protein, ICE-like apoptotic protease 5 Protein, Pro Caspase 8 Protein, FADD-like ICE Protein, FLICE Protein, MACH-alpha-1/2/3 protein Protein, MACH-beta-1/2/3/4 protein Protein

Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Requested From: 
Date Requested: 5/25/2018

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