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Human c-CBL Recombinant (GST) Protein LS-G27760

Ordering

Wt. Vol. Conc. Price
10 µg - - $415
Inquire for larger quantities
LSBio (USA Sales Only) LSBio (USA Sales Only)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular c-CBL Proteins

Human c-CBL Recombinant (His + GST) Protein - LS-G25547
E. coli Expression System
His + GST
Unpurified
Human c-CBL Recombinant (GST) Protein - LS-G27760
Wheat Wheat Germ Extract
GST
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

100% Guaranteed 100% Guaranteed
LS-G27760
Recombinant Protein
c-CBL
Human
126 kDa
MAGNVKKSSG AGGGSGSGGS GSGGLIGLMK DAFQPHHHHH
HHLSPHPPGT VDKKMVEKCW KLMDKVVRLC QNPKLALKNS
PPYILDLLPD TYQHLRTILS RYEGKMETLG ENEYFRVFME
NLMKKTKQTI SLFKEGKERM YEENSQPRRN LTKLSLIFSH
MLAELKGIFP SGLFQGDTFR ITKADAAEFW RKAFGEKTIV
PWKSFRQALH EVHPISSGLE AMALKSTIDL TCNDYISVFE
FDIFTRLFQP WSSLLRNWNS LAVTHPGYMA FLTYDEVKAR
LQKFIHKPGS YIFRLSCTRL GQWAIGYVTA DGNILQTIPH
NKPLFQALID GFREGFYLFP DGRNQNPDLT GLCEPTPQDH
IKVTQEQYEL YCEMGSTFQL CKICAENDKD VKIEPCGHLM
CTSCLTSWQE SEGQGCPFCR CEIKGTEPIV VDPFDPRGSG
SLLRQGAEGA PSPNYDDDDD ERADDTLFMM KELAGAKVER
PPSPFSMAPQ ASLPPVPPRL DLLPQRVCVP SSASALGTAS
KAASGSLHKD KPLPVPPTLR DLPPPPPPDR PYSVGAESRP
QRRPLPCTPG DCPSRDKLPP VPSSRLGDSW LPRPIPKVPV
SAPSSSDPWT GRELTNRHSL PFSLPSQMEP RPDVPRLGST
FSLDTSMSMN SSPLVGPECD HPKIKPSSSA NAIYSLAARP
LPVPKLPPGE QCEGEEDTEY MTPSSRPLRP LDTSQSSRAC
DCDQQIDSCT YEAMYNIQSQ APSITESSTF GEGNLAAAHA
NTGPEESENE DDGYDVPKPP VPAVLARRTL SDISNASSSF
GWLSLDGDPT TNVTEGSQVP ERPPKPFPRR INSERKAGSC
QQGSGPAASA ATASPQLSSE IENLMSQGYS YQDIQKALVI
AQNNIEMAKN ILREFVSISS PAHVAT
Wheat Germ Extract
Wheat
GST
Glutathione Sepharose
50 mM Tris-HCl, pH 8.0, 10 mM reduced glutathione
Store at -80°C. Avoid freeze-thaw cycles.
For research use only.

About c-CBL

P22681 NM_005188 NP_005179.2

CBL Protein, C-CBL Protein, Oncogene CBL2 Protein, RING finger protein 55 Protein, Proto-oncogene c-Cbl Protein, RNF55 Protein, CBL2 Protein, FRA11B Protein, NSLL Protein

Adapter protein that functions as a negative regulator of many signaling pathways that are triggered by activation of cell surface receptors. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including KIT, FLT1, FGFR1, FGFR2, PDGFRA, PDGFRB, EGFR, CSF1R, EPHA8 and KDR and terminates signaling.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
12.5% SDS-PAGE of human CBL stained with Coomassie Blue
 

Requested From: United States
Date Requested: 12/7/2016

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