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Human APEX1 / APE1 Protein (Recombinant) (Pro2-Leu318) - LS-G38639

Catalog Size Price
LS-G38639-10 10 µg Unavailable
LS-G38639-50 50 µg Unavailable
LS-G38639-500 500 µg Unavailable
LS-G38639-1000 1000 µg Unavailable

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100% Guaranteed
LS-G38639
Recombinant Protein
APEX1 / APE1
Human
35.62kD
Recombinant Human Apurinic-Apyrimidinic Endonuclease 1 is produced by our E. coli expression system and the target gene encoding Pro2-Leu318 is expressed.
Pro2-Leu318
MGPKRGKKGA VAEDGDELRT EPEAKKSKTA AKKNDKEAAG
EGPALYEDPP DQKTSPSGKP ATLKICSWNV DGLRAWIKKK
GLDWVKEEAP DILCLQETKC SENKLPAELQ ELPGLSHQYW
SAPSDKEGYS GVGLLSRQCP LKVSYGIGEE EHDQEGRVIV
AEFDSFVLVT AYVPNAGRGL VRLEYRQRWD EAFRKFLKGL
ASRKPLVLCG DLNVAHEEID LRNPKGNKKN AGFTPQERQG
FGELLQAVPL ADSFRHLYPN TPYAYTFWTY MMNARSKNVG
WRLDYFLLSH SLLPALCDSK IRSKALGSDH CPITLYLAL
E. coli
E. coli
None
Greater than 95% by SDS-PAGE
Not Tested
Less than 1.0 EU/µg protein (determined by LAL method).
Supplied as 0.2 µm filtered 10 mM HEPES, pH 7.4, 100 mM KCl, 50% Glycerol.
Store at less than -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
For research use only.

About APEX1 / APE1

P27695 NM_001641 NP_001632.2

APEX1 Protein, AP endonuclease class I Protein, AP lyase Protein, APE Protein, APE-1 Protein, APEN Protein, APE1 Protein, APEX nuclease Protein, Redox factor-1 Protein, AP endonuclease 1 Protein, APEX Protein, APX Protein, Protein REF-1 Protein, REF-1 Protein, REF1 Protein

Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 in DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents.

Requested From: 
Date Requested: 12/16/2017

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