Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
1. Measured by its binding ability in a functional ELISA. Immobilized mouse APCS at 10 µg/ml (100 µl/well) can bind biotinylated human Fibronectin Fragment 2 with a linear ranger of 0.625-5 µg/ml. 2. Measured by its ability to bind mouse CD64-AVI in a functional ELISA.
Lyophilized PBS, pH 7.4
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
APCS Protein, 9.5S alpha-1-glycoprotein Protein, Amyloid P component, serum Protein, Pentaxin-related Protein, PTX2 Protein, Serum Amyloid P Protein, Serum amyloid P-component Protein, SAP Protein
APCS / Serum Amyloid P / SAP is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin.