Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
AKAP7 Protein, A-kinase anchor protein 9 kDa Protein, A-kinase anchor protein 18 kDa Protein, AKAP-7 isoforms alpha and beta Protein, AKAP-7 isoform gamma Protein, AKAP 18 Protein, AKAP15 Protein, AKAP18 Protein, PRKA7 isoform gamma Protein, PRKA7 isoforms alpha/beta Protein
Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium.