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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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Human ABO Glycosyltransferase Protein (Recombinant His) - LS-G17387
Purified / Lyophilized / Endotoxin Level: Less than 1.0 EU/µg protein (determined by LAL method).
LS-G17387
Recombinant Protein
ABO Glycosyltransferase
Human
ABO Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 322 amino acids (54-354 a.a) and having a molecular mass of 37.4kDa.ABO is fused to a 21 amino acid His-tag at N-terminus and purified by proprietary chromatographic techniques.
E. coli
E. coli
His
Greater than 85% by SDS-PAGE
Not Tested
Not Tested
20 mM Tris-HCl, pH 8.0, 20 mM DTT, 20% glycerol, 20 mM NaCl.
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
ABO Protein, A3GALNT Protein, A transferase Protein, A3GALT1 Protein, B transferase Protein, ABO glycosyltransferase Protein, GTB Protein, NAGAT Protein
This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen.
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