Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
ABI1 Protein, Abelson interactor 1 Protein, Abl-interactor protein 1 long Protein, ABI-1 Protein, Abl-interactor 1 Protein, Abl interactor 1 Protein, Abl-binding protein 4 Protein, ABLBP4 Protein, NAP1BP Protein, Nap1 binding protein Protein, SSH3BP1 Protein, Nap1-binding protein Protein, E3B1 Protein, Eps8-binding protein Protein, Interactor protein AblBP4 Protein, SSH3BP Protein
May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac.