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E. coli DIABLO / SMAC Protein (Ala56-Asp239) - LS-G48337
E. coli DIABLO / SMAC Protein (Ala56-Asp239) - LS-G48337
None
Purified / Lyophilized / Biologically Active
LS-G48337
DIABLO / SMAC
E. coli
Ala 56-Asp 239
None
Greater than 90% by SDS-PAGE
Measured by its binding ability in a functional ELISA.Immobilized recombinant human SMAC-His (Cat:10339-H08E)at 10 µg/ml (100 µl/well) can bind recombinant human XIAP-AVI with a linear range of 0.125-1.0 µg/ml.
Not Tested
Lyophilized from sterile PBS, pH 7.4
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
DIABLO Protein, DFNA64 Protein, DIABLO-S Protein, Diablo homolog, mitochondrial Protein, SMAC3 Protein, Mitochondrial Smac protein Protein, SMAC Protein
Second mitochondria-derived activator of caspase (SMAC) has been implicated in the activation of apoptosis in response to cell stress. SMAC promotes CASP9 activation by binding to IAPs and removing their inhibitory activity. The inhibitor of apoptosis proteins (IAPs) regulate programmed cell death by inhibiting members of the caspase family of enzymes.
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