Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Measured in a cell proliferation assay using human umbilical vein endothelial cells(HUVEC) (Conn, G. et al. 1990, Proc. Natl. Acad. Sci. USA 87:1323.). The ED50 for this effect is typically 10-50 ng/ml.
Lyophilized from sterile pH 7.92 100 mM glycine , 10 mM NaCl.
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.