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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
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PathPlusTM BCL2 / Bcl-2 Antibodies
BCL2 is a regulator of apoptosis that functions to promote cell survival and inhibit the actions of proteins involved in the apoptosis cascade. Overexpression of BCL2 has an oncogenic effect and is correlated with increasing the lifespan of B cells. Cancers that are positive include follicular lymphomas due to t(14,18)(q32;q21), which brings BCL2 gene adjacent to the active immunoglobulin heavy chain (IgH) gene. In addition, positive staining is expected in diffuse large B-cell cell lymphomas and myelodysplastic syndrome. In normal tissues, positive expression is found in mantle zone B cells, germinal center T cells, and several other tissues. Cell Death and Differentiation 25:65, 2018; Am J Surg Pathol 2011;35:1691, Am J Surg Pathol 2009;33:591

4 PathPlusTM Antibodies
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BCL2 / Bcl-2 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
Mouse Recombinant Monoclonal [clone rBCL2/782] (IgG1,k) to Human BCL2 / Bcl-2
Human
Flo, IF, IHC-P, WB
Unconjugated
100µg   200µg/ml   $462.00
BCL2 / Bcl-2 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
Mouse Recombinant Monoclonal [clone rBCL2/796] (IgG1,k) to Human BCL2 / Bcl-2
Human
Flo, IF, IHC-P, WB
Unconjugated
100µg   200µg/ml   $462.00
BCL2 / Bcl-2 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
Rabbit Recombinant Monoclonal [clone BCL2/2210R] (IgG) to Human BCL2 / Bcl-2
Human
IHC-P, WB
Unconjugated
100µg   200µg/ml   $462.00
BCL2 / Bcl-2 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
Rabbit Recombinant Monoclonal [clone BCL2/1878R] (IgG) to Human BCL2 / Bcl-2
Human
IHC-P, WB
Unconjugated
100µg   200µg/ml   $462.00

Viewing 1-4 of 4 items