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| Catalog Number | Size | Price |
|---|---|---|
| LS-B14510-50 | 50 µl (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human TFE3 Antibody (Internal, IHC, IF, WB) LS‑B14510
PathPlus™ Polyclonal Rabbit anti‑Human TFE3 Antibody (Internal, IHC, IF, WB) LS‑B14510
Note: This antibody replaces LS-C352925
Antibody:
TFE3 Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC, IHC-P, ICC, IF, WB
Reactivity:
Human, Mouse, Rat, Bovine, Dog, Pig
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
TFE3 Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC, IHC-P, ICC, IF, WB
Reactivity:
Human, Mouse, Rat, Bovine, Dog, Pig
Format:
Unconjugated, Unmodified
Specifications
Description
TFE3 (Transcription factor binding to IGHM enhancer 3) is a nuclear protein that promotes the expression of genes downstream to TGF-beta signaling. Chromosomal translocations between this gene (located on Xp11.2) and other genes promote growth and proliferation, and oncogenic activation. Translocation or overexpression of this gene has been implicated in renal cell carcinoma, lung adenocarcinoma, alveolar soft-part sarcoma, papillary thyroid carcinoma, melanoma, and mesotheliomas. It is expressed in a wide variety of tissues, and is nuclear in localization.
References: AmJSurgPathol 2009 33:1894; Histopath 1993, 23:439
Target
Human TFE3
Synonyms
TFE3 | BHLHe33 | Transcription factor E3 | RCCX1 | TFEA | RCCP2
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bovine, Dog, Pig
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the central region of human TFE3.
Epitope
Internal
Specificity
Recognizes endogenous levels of TFE3 protein.
Applications
- IHC
- IHC - Paraffin (1:100)
- ICC (1:100 - 1:500)
- Immunofluorescence
- Western blot (1:500 - 1:1000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.3, 0.01% Sodium Azide, 30% Glycerol
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TFE3
Validation
Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ TFE3 Antibody (Internal) for IHC, ICC, IF/Immunofluorescence, WB/Western LS-B14510 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC - Paraffin, Western blot
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC - Paraffin, Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/16/2024
Date Requested: 4/16/2024
